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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

Edgar Wright’s Baby Driver is one of the most entertaining thrill rides of this year, this decade. This century.
Gitanjali表示,她想要进一步改善改设备,这样它最终就能进入市场了。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Coke's Kent is not the only chief executive who spoke out in 2013 about the merits of immigration reform for big business.
除此之外,美国还将举行更为传统的庄重纪念活动,其中包括奥巴马总统在与美国首都华盛顿一河之隔的阿灵顿国家公墓向无名战士墓敬献花圈。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

来自中国、日本、美国、德国、葡萄牙和伊朗等国的1300名选手设计制造了各自的足球机器人。在比赛中,一队里有五名机器人,它们依靠事先设定的程序自主运动,而不能受场外人员操控。

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 西宁市住房公积金政策有调整
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

Carve out a place at home that is your study space. If you've got a family around you, make sure everyone understands that when you're in that space, you're not to be interrupted unless the house is on fire.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

2014年,演员蒂尔达·斯文顿(Tilda Swinton)在四部电影中戴着假牙:《零点定理》(The Zero Theorem)、《布达佩斯大饭店》、《唯爱永生》(Only Lovers Left Alive),以及奉俊昊导演的《雪国列车》(Snowpiercer)。在最后这部惊悚片中,斯文顿饰演残酷、狡猾的梅森部长(Minister Mason),她戴着一副大大的眼镜,有一口庞大、丑陋的牙齿。
3.贾君鹏,你妈妈喊你回家吃饭。
10. You've just been acting weird, OK?
1.Mitsubishi. Brand love: -12% / Rank: 360

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

But the UK courts may land a heavy blow on ride-hailing app Uber. In 2017, the California-based company failed to persuade an appeal judge that two of its London drivers are independent contractors. In 2018, the test case will go to the Court of Appeal and possibly to the Supreme Court. If Uber loses the case and is told to assume the responsibilities of an employer, the implications will ripple far and wide.
谎言4:太感谢了!我很喜欢!说谎原因:告诉别人他们送的礼物一团糟会让我看起来像是冷血的混蛋。
Her predecessor David Cameron placed fifth in CNNMoney's previous ranking in March 2015 with his salary of £142,500, then worth $214,800. May is only seventh.
Two days ago here in Brazil, we were shocked when we spent some time with some children living on the streets. And this is what one child told us: "I wish I was rich and if I were, I would give all the street children food, clothes, medicine, shelter and love and affection." 在巴西,我被2天前见到的情景震惊了,那时我和当地的小孩在玩耍,其中一个小孩说:“我希望我能富裕起来,然后我会给这个街道所有的小孩饭吃,给他们衣服穿,医疗,住房和爱”。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

节目3 歌曲《十二生肖》,王力宏

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

reflection

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

New employees at the company's Tulsa headquarters have little time to be shy: on their first days, they're seated at desks with a tub of candy. Colleagues often stop by and introduce themselves while grabbing a snack.
Will the Saudi Aramco public offering debut on an international market

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

Best chance: If there are nine or 10 best picture nominees, it could grab a spot. Jordan Peele's screenplay looks certain to be recognized.
乌拉圭代表了一个更令人感到好奇的例子,国家队的球员是伪装成小人物的足球贵族。像比利时一样,这也是一个相对年轻的国家,但在赛场上它则是一名老手。他们曾两次赢得世界杯,第一次是1930年首届世界杯,第二次是在1950年,当时巴西是东道主。后来的那次被称为“马拉卡纳之殇”,一场人们在今天依然还记得的国家悲剧,当时巴西在创世界记录的20万(或许更多)球迷面前被压垮了。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
From the themed collection: 定制家具或将成未来消费热点
Open Access Review Article

Diagnostic technologies for COVID-19: a review

在苹果公司外面,摆着一台显示乔布斯照片的iPhone ,用以寄托对这位苹果创始人和前CEO的哀思。2011年10月6日,旧金山,苹果总部
The Spring Festival Travel Rush, also known as Chunyun in Chinese, or Spring Festival Travel Season / Transportation Peak is considered to be the largest annual migration.It is the special period when China faces an extremely high traffic load, which results in great transportation problems, especially on the railway services.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

8.Wheel Skates
Profit at property insurers fell 43.39 per cent year-on-year to Rmb33.7bn. For life insurance firms it dropped 65.6 per cent to Rmb54.2bn, while for reinsurers it fell 58.8 per cent to Rmb4.4bn.
尽管随着租赁成本的上升和失业率的下降,薪酬最终会会上升;商人们将会在招聘劳动力上付出更多的成本而且还有可能由于缺乏员工以增加产量而导致销售量下降的风险。
布朗克斯大广场区或皇后区埃尔姆赫斯特(Elmhurst)的业主们,即将迎来急于寻找下一个未开发市场的买家们的新关注。“你什么时候听到别人谈论过布朗克斯的金斯布里奇(Kingsbridge)?”霍尔斯特德房地产公司的拉米雷斯问,“聪明人正在涌向那里,以实惠的价格买下房子。”

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
From the themed collection: 房企业绩在7月出现回落
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Statistics from another market research firm, Counterpoint, indicate that China shipped 465 million smartphones over the last year, accounting for nearly one-third of the global volume.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

The survey of 11,500 workers by Chinese employment agency Zhaopin found that 50.9 per cent did not get an annual bonus at the end of 2016. Another 9.6 per cent were told their bonus had been delayed until after the new year holiday.
大小:6364平方英尺(约591平方米)

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

另一名来自美国的毕业生写道,来自世界各地的知识的丰富性和深度为课程带来了巨大的价值,他补充称,“鉴于这里汇聚着众多的文化和经验,有关贿赂的课堂道德讨论不像典型的美国学校那样枯燥。”

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
From the themed collection: 全国新型职业农民超过1500万
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

优秀老板看起来都会拥有的一个关键是:他们都是解决问题的高手。他们不仅能够发现问题,并能头脑风暴出成功创新的方法来解决问题。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
From the themed collection: 城乡一体化校最高可获资助200万元
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

《花千骨》
得益于网络游戏产业的快速增长,网易公司创始人丁磊的财富翻倍至960亿元,超越了百度公司董事长李彦宏,在IT富豪榜上排名第三。
In the past decade, only three blue diamonds of 10 carats or more with the same vivid grading for intensity have been sold at auction, all weighing less than 12 carats and none flawless, he said.
Meanwhile, in an unfortunate red carpet faux pas, Pink and Shakira both showed up in the same Balmain dress.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

除了P2P贷款领域发展迅速以外,今年还涌现出一些网络银行和贷款机构——比如腾讯(Tencent)的微众银行(WeBank)、阿里巴巴(Alibaba)的网商银行(Mybank),以及蚂蚁金融(Ant Financial)的芝麻贷(Sesame Credit)。
Marco Montanari, the head of passive asset management for Asia-Pacific at Deutsche AM, agrees that fundamental changes to distribution must be made before the Asian ETF market can move to the next level.
如果观众还不知道这部影片是以20世纪80年代初为背景,那看一眼安娜的直刘海就知道了。她留着齐肩长发,刘海以外的部分在脸庞四周形成微微弯曲的弧度。这个造型很简单,但对这个女人来说显得很有力量,她丈夫艾贝尔(奥斯卡·伊萨克[Oscar Isaac]饰)经营取暖油生意,不过她的过去更为复杂。
第一架无线电操纵的无人驾驶飞机可追溯到1916年。英国发明家阿奇博尔德·洛设计并试飞了第一架无人遥控飞机。它是为了反攻德国齐柏林飞艇而制作的,在第一次世界大战中参与了对地面攻击的战斗。无人机由木和锡制成,它的机翼用的是其他双翼飞机的较低机翼。总的来说,无人机是有些失败的,因为它的引擎噪音干扰了无线操作。1916年,索普威斯飞松公司也尝试制作无人机,他们将无线电设备放置在无人机的尾部,这样引擎就不会干扰到它的信号。但因一次地面上的意外事故,他们的无人机再未起飞:当洛操作无人机飞到高级军官面前时,他原本计划会在1917年再次试飞无人机。但无人机从卡车的后面发射后,飞了一段时间便因引擎故障而坠毁,差点要了在场的军官的命。
中国最高质量监督部门日前表示,去年通过网购平台出口到中国的消费品,超过40%是不合格的。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
From the themed collection: 新型建材造就室内外温差12℃
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

Lisa Stone
Investigators have arrested one youth and one 18-year-old in connection to the July 9th shooting.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

其实,它体现在所有品牌上,它们把六七十年代的服装搬到当季店铺里,包括阿尔伯特·菲尔蒂(Alberta Ferretti)、璞琪(Pucci)和艾绰(Etro)。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

超级大坏蛋们将受命保护人类——这就是《自杀小队》的主旨。 一个名叫“A.R.G.U.S”的政府机构招募了一些罪犯帮它执行危险任务,罪犯们将得到的报酬是减刑。这支特遣小队的成员有小丑、死亡射手、哈利·奎恩、回旋镖队长、杀人鳄以及DC漫画宇宙里的其他坏家伙。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

Mr. Murray came to her with a full beard, so she was able to shape it into the thick, bushy mustache pictured here. “Bill has never worn that look before,” Ms. Hannon said, “so it was lovely to get something new.”
The Democratic party's would-be challenger, Republican frontrunner Donald Trump, responded on Fox News, accusing Clinton of pandering to female voters.
道·哈德森,学院理事会执行官
Sonneborn says he's been dismayed not only by what he sees as Trump's troubling decisions and juvenile moments but also by the president's response after a counterprotester was killed during the August white nationalist rally in Charlottesville, Virginia — which is what cemented Sonneborn's decision to seek office.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
From the themed collection: 新华社:央企整体负债率稳中有降
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

Episodic memory is also known as long-term memory, and the researchers approached the study of exercise in a different manner than previous studies. Other studies examined the impact of aerobic exercise conducted over many months, but this study simply asked participants to lift weights a single time. During the test, half of the participants were asked to use a weight machine before recalling a series of images they were shown at the start of the test. The other half of the participants were also asked to recall the images but without having engaged in any strenuous activity before the recall session. In demonstrating the memory improvement for the participants who engaged in just a single session of weight lifting, the researchers were able to show that improving one's memory through exercise didn't take hours of dedication in the gym. The next time you have the opportunity to lift weights or someone tries to convince you to join the gym you might just want to take him or her up on the offer.
No one since Michael Haneke has enjoyed cinematically dissecting social conventions as much as Greek film-maker Yorgos Lanthimos. His The Lobster took Cannes by storm two years ago with its scathing look at a society that turns adults into animals if they cannot find a romantic partner within 45 days – it was our world but pushed toward the outermost limits of groupthink and conformity. Now he’s back with The Killing of a Sacred Deer, a domestic thriller about a surgeon (Colin Farrell) and his wife (Nicole Kidman), also a doctor, who befriends a fatherless teen named Martin. The boy seems determined to expose the family’s secrets and unmask a terrible trauma from their past. Is this film about how domestic (and perhaps societal) tranquility sometimes depends on shared, agreed-upon lies? Either way, prepare to be unnerved. Released November 9 in Denmark, November 16 in Russia and November 30 in China's Hong Kong. (Credit: A24)
曾在许多公司里面工作过----大公司或小公司----我看到过很多的方法有些起作用,有些并不起作用。
de去掉,but。去掉but?导演Z(平静):你可以上台了。女演员F:but我还没准备好呢?Z(有点儿烦):哪那么多事儿呀,快点儿!F:but我这可是第一次!Z(强忍):谁没有第一次呀,快!F:but…,Z(已经怒了):哪XX那么多but呀,全都给我de掉,再不上去我就X人了!!!

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

克里斯托弗诺兰的这部二战题材电影可能就是最佳影片的领跑者。
《哈利·波特》粉们,福利来啦!该片是《哈利·波特》前传,讲述了纽特·斯卡曼德在老纽约的冒险经历。该片根据《哈利·波特》中霍格沃兹学院的同名教科书改编而成。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

亚太地区票房增长了13%,是推动国际票房增长的主力,而中国贡献了整个亚太地区近半票房。
《弗鲁特维尔车站》(Fruitvale Station)是另一部出色的故事片处女作,由瑞安?库格勒(Ryan Coogler)执导。这部影片的主题是赤手空拳的22岁黑人奥斯卡?格兰特(Oscar Grant)在加州奥克兰与一名白人交警发生冲突而遭到误杀,这本来可以成就一部纪录片。库格勒有更好的想法,将这个真实事件加以戏剧化改编,并在很大程度上进行了虚构,讲述了奥斯卡死亡前一天的生活。饰演这个角色的是迈克尔?乔丹(Michael Jordan),他的表演能让你心碎,也能令人欢乐不已,有时是两者兼具。
根据中国海关总署(General Administration of Customs)发布的数据,12月份以美元计的出口额同比减少6.1%至2094.2亿美元。这一跌幅比经济学家预期的中数多了2.1个百分点,也大于11月份修正后1.6%的跌幅(修正前该数字为增长0.1%)。
Against: Opening so early in the year outside of awards season could hinder its chances.
在经过了漫长的海选和五天紧张的半决赛之后,11位候选选手中其中一位成为了第八季英国达人秀2014年的冠军。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

8.身着平底鞋禁止入场,是吗?
smart
4=true

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

别了,《广告狂人》(Mad Men)。别了,那些追踪每集情节(更重要的是,每集服装)的博客和粉丝网站。
单词mortality 联想记忆:

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

infinite
来源:前十网
The blocks of flats which were up to 12 storeys high in the city of Wuhan are making way for a huge new business district including a 707-metre tall skyscraper.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
From the themed collection: 调控政策减少 楼市会回温吗?
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

vt. 安慰,使
周边环境:斯托宁顿位于康涅狄格州东南部的小纳拉甘西特湾(Little Narragansett Bay),从哈特福特(Hartford)和罗德岛的普罗维登斯(Providence, R.I.)开车约1小时可达,从纽约市开车约3小时。这里曾是一个具有悠久历史的繁忙港口,至今仍然保留着一支商业捕鱼船队,有几个分布着殖民式和联邦式建筑的历史区,以及一个繁荣的航海社区。在该镇的一端有个小型的公共海滩,而在另一端罗德岛的沃奇·希尔(Watch Hill)则有个大得多的海滩,开车大约20分钟可到。这栋希腊复兴式房屋带有此类建筑必不可少的爱奥尼亚柱和山形墙上的扇骨半圆窗,房屋就坐落在市镇中心。
例如,美国和亚洲向投资者推介产品的方式存在明显区别。在亚洲,很大比例的基金(一些人估计为90%)是以佣金为基础。这对ETF不利,因为它们在股票交易所公开交易,在结构上不便向可能推荐它们的银行、券商或理财顾问支付佣金,这与该地区的共同基金行业不同。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

8. 赤脚能够提高记忆力

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
From the themed collection: 深圳:建筑废弃物去向可“追踪”
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

After rising every year since 2008 global gold supply plateaued last year, according to the World Gold Council. In China, the world’s biggest producer, it fell by a record 9 per cent, the second time output has fallen in the country since 1980.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

“我试图做到的是继承他的衣钵,写一本典型的伊恩·弗莱明式的007小说。”
9.Priyanka Chopra

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

Why was I so confident that there would be no war in east Asia, either in the East China Sea or the South China Sea? The simple answer is that I know the Asian dynamic. While many Asian neighbours will make angry nationalist statements (and they have to do so to manage popular nationalist sentiments), they are also careful and pragmatic in their deeds.
4.嘘声不仅仅是个手势
然而,今年该项目仅排在第8位。
单词inspection 联想记忆:

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

林怡仲预测道,下半年A股IPO的数量或将维持与上半年相当,预计2016年全年A股IPO为120宗左右,融资规模在600-800亿元人民币左右。
这是中国首次占据榜单前三甲以及在前10强中占了5名。中国工商银行连续两年占据第1名的宝座,中国建设银行次之,而且中国农业银行向上移动了5名成为第3名。这三大银行与排在第9名的中国银行一起跻身前10强,中国银行是“四大国有银行”中的另一个成员。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
From the themed collection: 稳投资 有储备有信心
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

A study cited in an article from Harvard University suggests your diet could have a significant impact on your memory as you age. Scientists at Brigham and Women's Hospital published a study within the "Annals of Neurology" that suggested women who ate high levels of saturated fat in foods like red meat and butter didn't perform as well on memory tests than women who regularly consumed less saturated fat. Researchers haven't yet discovered the connection between saturated fat and memory, but they hypothesize it could have something to do with a person's genes. Scientists and doctors have long recommended that patients work to control their cholesterol levels as they age to protect the memory during the aging process.
7.助听器

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

com共同+plex重叠→全部重叠→复杂的

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

莱昂纳多·迪卡普里奥和嘎嘎小姐在今年金球奖拔得头筹。
4.British people may seem to apologise a lot, but it doesn't quite mean the same thing here. In the UK, "I'm sorry" actually means either a) I didn't hear you; b) I didn't understand you; or c) I both heard and understood you, and I think you're an idiot.
Unfortunately for May, the big drop in the pound since the Brexit vote means her salary has plunged in dollar terms.
If you have a question, come to my office. Don't corner me in the bathroom.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

galaxy
“Climate change is perhaps the major challenge of our generation,” said Michael H. Freilich, director of earth sciences at NASA, one of the agencies that track global temperatures.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

Among the top 50 richest women in the world, entrepreneurs from the Chinese mainland account for 56%.
难怪现代和当代艺术品拍卖市场的主要玩家佳士得拍卖行把自己的早期绘画大师作品重新宣传为“古典艺术品”。它将于明年4月(原先的计划是明年1月)在洛克菲勒中心(Rockefeller Center)举办早期绘画大师作品及其他历史作品拍卖会,其中包括20世纪作品专题拍卖会。周五(12月18日),佳士得称,它的“古典艺术品”拍卖计划将于明年7月在伦敦公布。
这张专辑等于是一次直截了当的暗示,提醒着我们,不论什么时候,只要霉女王想要,她就能拿回自己在流行音乐界的领先地位。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

这枚奖牌拍出的高价远远超过了该拍卖行预计的成交金额——5万美元到10万美元。此前,仅有1903年诺贝尔和平奖奖牌在1985年被拍卖,拍得将近1.7万美元。
The Aftermath of Zika Virus
"This is something we believe is really important for the future of our country,"Facebook (FB, Fortune 500) CEO Mark Zuckerberg said in August.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
From the themed collection: 多个热点城市二手房价出现下调
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

又到了一年盘点的时候了,扬子晚报上传了一段名叫今年中国网络九条最热流行语的视频,盘点了如下几条流行语。
Song “Wind Blowing In The Wheat Field” (Li Jian and Sun Li)

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

In news that should come as little surprise to global air travelers, Singapore's done it again.
《失常》,导演查理·考夫曼(Charlie Kaufman)与杜克·约翰逊(Duke Johnson)。
9.千万别相信民调

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

Wearing a black leotard and curled hairpiece, beauty queen Bobbi Boyden shakes her hips and blows kisses to the audience as part of her routine.
facilitate

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
From the themed collection: 杭州:申花一楼盘首开遭遇滑铁卢
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

华盛顿:到十月份底,印度减持美国政府债券到775亿美元,尽管作为世界上最大经济体的美国的经济在稳步的上升。
When you need help, reach out to people in your networks – that’s what they’re there for. Whether you need a confidence-boosting pep talk or advice about building your technical experience — your mentor, your colleagues, and your manager can help. You may not know how to do something today, but chances are you’re smart enough to find someone who can help you learn it. And once you do, don’t unfasten your seatbelt – there’s always going to be another challenge headed your way.
男性使用这个密码的几率是女性的2.8倍。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

1.Photography: 22.3 percent increase

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

"Sydney's housing prices shot up because foreign investors are buying trophy assets, in places like Bondi," says Elliot.
不会。傻子才会去预测足球比赛的结果。最好是作事后诸葛亮。目前已经举办过20届世界杯。其中,巴西(5次捧杯)和德国(4次捧杯)是决赛常客。主场优势有所帮助,东道国赢得了6次奖杯。但是明年的世界杯将在俄罗斯举行,而这位东道主在参赛队伍中排名垫底。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Good luck and great success in the coming New Year.
坚持依法全面履职。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
From the themed collection: 中国瓷砖行业路在何方
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
From the themed collection: 民宿何时不再被“民诉”
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

The improvements in education levels mirrored the development of China's education system. Independent research into China's education situation showed that overall education development was better than the world average last year, Yuan Guiren, minister of education, said in March.
potential

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

Are you looking at the clothes? Eva Longoria Parker stripped off as she posed with husband Tony to advertise the London Fog fashion line. Eva Longoria Parker s
据中国电影监察机构日前表示,2016年中国票房总额有望超过2015年的440亿元人民币(折合68亿美元)。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

高盛将大派红包,饱受各方抨击一个月,然后静悄悄地干回自己的老本行--挣钱。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

恭祝健康、幸运,新年快乐。
You can read the full list of stories, but here are the top five:
死者是一名19岁的女孩,被称为郭玲玲(这可能是化名),据称她未经许可去卫生间后被所谓的导师反复拳打脚踢。验尸报告显示,死亡原因是因为颅骨受伤和脑损伤。
Experts say that 2016 was a remarkable year for the Chinese film industry as it realized growth while facing multiple challenges including the rapid development of the internet, the increasingly sophisticated tastes of Chinese audiences, and the economic downturn in the country.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Type D personalities usually have a low self-esteem and a great fear of disapproval and this is the primary reason that prevents them from opening up to others.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

Here are five things consumers and investors can count on (probably) in 2015:
That's particularly striking in Brazil, with its highly mixed population that has more blacks than any country with the exception of Nigeria. More than half of Brazil's population self-identified themselves as black or of mixed-race in the 2010 census.
单词charming 联想记忆:

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

“这不是可持续的增长,因为它们并未被租出去,当地市场的喊价者们并不会购买。”
因此,D型人格的人并不是缺乏社交兴趣,而是可能对别人感兴趣,但又害怕接近别人,因为他们害怕被拒绝。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

据上周一发布的全球创新指数显示,中国成为首个跻身世界最具创新力经济体25强的中等收入国家。
8月7日

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

2013 Rank: 3

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Friends wasn't known for being the most diverse show on television at the time, since the cast was comprised of almost entirely white actors. None of the main characters were anything other than "mainstream." Even the acknowledgement of Ross's first wife Carol being a lesbian was met with jokes about sexuality (mostly from Joey), and sexist comments were frequently incorporated into the script.
[m?:'t?liti]
每一次我们詹姆斯已经达到了顶点,詹姆斯就会拿出更好的表现超过那个顶点。他那无所不包的各项技巧,是詹姆斯辛苦训练的证明。你可以嘲笑他所提发布的所有Instagram录像,但这些都是他仍然能够做到这一点的真正原因;詹姆斯从来不轻视他的每一场比赛,一次都没有。结果便是晚上一次又一次无可比拟的表演。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
From the themed collection: 2015年前4月涂料利润增长14.3%
Paper

Length-scale dependence of protein hydration-shell density

3. Enlisted military personnel
Chris Washington, played by London-born Daniel Kaluuya, is drawn into the sinister underbelly of a small American community.
The year before, Taiwanese anti-China protesters chose the sunflower as the symbol for their cause.
线索可能隐藏在价格之中:H股很便宜。H股指数市盈率为7倍,低于西班牙(该国失业率达到22%)、巴西(该国依赖大宗商品,因而也依赖中国)以及受中东乱局影响的土耳其和埃及。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

morality
Subdivided flats smaller than 100 square feet (9 square meters) can rent for $385 in the Asian city.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

仅在2001年,全球就约有55.7万人被谋杀。而到了2008年,这个数据就减少了28.9万人。如今,全球的谋杀率已经下降了75%。
始终保持廉洁本色。
我们坐在这里指点江山,告诉那些球队“你们没指望了,赶紧输球摆烂吧!”这是很容易的,但是我们并不是那些在为球队门票和广告殚精竭虑的家伙们。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

About this collection

单词addition 联想记忆:
《战地神探》(Foyle’s War),acorn.tv,2月2日播出。去年流媒体服务网络Acorn TV放完了《大侦探波洛》(Agatha Christie’s Poirot)的最后三集,如今又带来另一部传统英国推理剧,这部超级剧集在英国已经拍到第九季,在美国还是首次播出。迈克尔·基臣(Michael Kitchen)在剧中饰演克里斯托弗·弗伊(Christopher Foyle),一位可敬而又狡黠的侦探,这部剧多年来从一部“二战”后方警探剧演变成勒卡雷(le Carré)式的冷战惊悚剧。新的几集中有纽伦堡审判以及英国在巴勒斯坦所扮演的角色。

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